Life Sciences
Investigators at University of Pittsburgh publish new data on life sciences
Published in Obesity and Diabetes Week, September 1st, 2008
Current study results from the report, 'Effects of chronic central leptin infusion on proopiomelanocortin and neurotensin gene expression in the rat hypothalamus,' have been published. According to recent research published in the journal Neuroscience Letters, "Leptin signaling in the hypothalamus is critical for normal food intake and body weight regulation. While hyperleptinemia in obese people suggests a state of leptin resistance, the mechanism is not clearly understood."
"In a rat model of central leptin infusion in which animals develop resistance to the satiety action of leptin, orexigenic peptide producing neuropeptide Y neurons in the hypothalamus...
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