Type 2 Diabetes
New data from R. Scott et al illuminate research in type 2 diabetes
Published in Obesity and Diabetes Week, October 27th, 2008
In this recently published article, scientists in the United States conducted a study "To assess the addition of sitagliptin to ongoing metformin therapy in patients with type 2 diabetes who were inadequately controlled [haemoglobin A(1c) (HbA(1c)) 7-11%] on metformin monotherapy. Patients (n = 273) on metformin (>= 1500 mg/day) were randomized to receive the addition of once-daily placebo, sitagliptin 100 mg or rosiglitazone 8 mg in a 1:1:1 ratio for 18 weeks."
"The efficacy analysis was based on the all-patients-treated population using an analysis of co-variance with change in HbA(1c) from baseline as the primary endpoint. The mean baseline HbA(1c) was 7.7% for...
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