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Obesity

Recent findings from University of Missouri, Medical Department highlight research in obesity

Published in Obesity and Diabetes Week, November 3rd, 2008

According to recent research from the United States, "Angiotensin converting enzyme (ACE) catayzes the formation of angiotensin I to angiotensin II. A polymorphism has been identified in intron 16 in which a 287 base-pair alu sequence was found to be present (inertion or I) or absent (deletion or D) in the population."

"ACE and the components of the renin-angiotensin system are expressed in adipose tissue and therefore the I/D polymorphism with ACE may be associated with obesity. This study involved genotyping two groups with differing body mass indexes (BMI <= 25 and BMI >= 30) that were composed primarily of middle-age Caucasian subjects (n=421). The male groups...

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