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Prostate Cancer

Research results from Duke University update understanding of prostate cancer

Published in Obesity and Diabetes Week, November 10th, 2008

According to recent research from the United States, "To indirectly test the hypothesis that prostate-specific antigen (PSA)-based screening is biased against obese men due to haemodilution of PSA, and thus results in delayed diagnosis and poorer outcome beyond the biological link between obesity and aggressive prostate cancer. We sought to examine the association between body mass index (BMI) and the outcome of radical prostatectomy (RP) separately for men with PSA-detected cancers (cT1c) or with abnormal digital rectal examination (DRE) findings (cT2/T3), and stratified by year of treatment, using two large databases."

"We conducted a retrospective cohort study of...

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