Scripps Research Institute

Scripps research scientists develop a new strategy to fight obesity

Published in Obesity and Diabetes Week, November 10th, 2008

The antibody works against the gastric hormone ghrelin (pronounced "grell-in"), which has been linked to weight gain and fat storage through its metabolic actions. These findings point towards a potentially novel treatment for obesity that would interfere directly with the some of the biological mechanisms determining weight.

The study is being published the week of October 27, 2008, in an advance, online Early Edition of the journal Proceedings of the National Academy of Sciences (PNAS).

In the study, which was led by investigators Kim Janda and Eric P. Zorrilla of The Scripps Research, the antibody catalyst GHR-11E11 led to a higher metabolic rate...

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Source: Obesity and Diabetes Week (2008-11-10)

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