Obesity and Diabetes
Research reports from M. Lehtihet and co-authors provide new insights into obesity and diabetes
Published in Obesity and Diabetes Week, November 24th, 2008
According to recent research from Stockholm, Sweden, "IGFs (insulin-like growth factors), which in an unbound form induce glucose and amino acid uptake, circulate bound to IGFBPs (IGF-binding proteins), which modulate their bioavailability and activity. The aim of the present study was to examine the effect of a standard meal [2301 kJ (550 kcal)] on the serum levels of IGFBP-1 in obese patients with T2DM (Type 2 diabetes mellitus), non-obese patients with TIDM (Type 1 diabetes mellitus) and healthy controls, using the artificial pancreas (Biostator (R)) to obtain a normal glycaemic response to the meal."
"IGFBP-1 levels decreased by 50% over 2 h following the meal at a...
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