Stem Cell Research

Findings from Rockefeller University advance knowledge in stem cell research

Published in Obesity and Diabetes Week, December 22nd, 2008

"The increased white adipose tissue (WAT) mass associated with obesity is the result of both hyperplasia and hypertrophy of adipocytes. However, the mechanisms controlling adipocyte number are unknown in part because the identity of the physiological adipocyte progenitor cells has not been defined in vivo," scientists in the United States report.

"In this report, we employ a variety of approaches, including a noninvasive assay for following fat mass reconstitution in vivo, to identify a subpopulation of early adipocyte progenitor cells (Lin(-): CD29(+): CD34(+): Sca-1(+): CD24(+)) resident in adult WAT. When injected into the residual fat pads of A-Zip lipodystrophic...

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Source: Obesity and Diabetes Week (2008-12-22)

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