Columbia University Medical Center

Cardiac stent patients with diabetes may benefit from drug that counteracts the effects of leptin

Published in Obesity and Diabetes Week, December 29th, 2008

The naturally high levels of leptin in diabetic patients may reduce the effectiveness of drug-eluting stents used to treat heart blockages, but using a chemical that differs from the one commonly used to coat stents could counteract this effect.

The work by researchers at Columbia University Medical Center could potentially improve outcomes in diabetics who get stents, they say. Though drug-eluting stents reduce the chance coronary arteries will become blocked again, clogged stents are still more common in diabetic patients than in the general population. About 250,000 Americans with diabetes receive drug-eluting stents every year.

A hormone commonly...

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Source: Obesity and Diabetes Week (2008-12-29)

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