Obesity and Diabetes
Study findings from Yale University, Department of Orthopaedics broaden understanding of obesity and diabetes
Published in Obesity and Diabetes Week, January 26th, 2009
Current study results from the report, 'Increased energy expenditure and insulin sensitivity in the high bone mass DeltaFosB transgenic mice,' have been published. "Obesity and osteoporosis are major health issues affecting millions of individuals. Transgenic mice overexpressing DeltaFosB, an activator protein-1 transcription factor, under the control of the enolase 2 (ENO2) promoter exhibit both an increase in bone density and a decrease in adipose mass," scientists in the United States report.
"Here we demonstrate that DeltaFosB overexpression increases fatty-acid oxidation and energy expenditure, leading to a decrease in adipocyte size and adipose mass. In addition,...
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