Ischemia

Scientists at Nagoya University, Medical Department publish new data on ischemia

Published in Obesity and Diabetes Week, March 9th, 2009

"Caloric restriction (CR) can extend longevity and modulate the features of obesity-related metabolic and vascular diseases. However, the functional roles of CR in regulation of revascularization in response to ischemia have not been examined," researchers in Nagoya, Japan report.

"Here we investigated whether CR modulates vascular response by employing a murine hindlimb ischemia model. Wild-type (WT) mice were randomly divided into two groups that were fed either ad libitum (AL) or CR (65% of the diet consumption of AL). Four weeks later, mice were subjected to unilateral hindlimb ischemic surgery. Body weight of WT mice fed CR (CR-WT) was decreased by 26% compared...

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Source: Obesity and Diabetes Week (2009-03-09)

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