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Pancreas

Researchers from Park University discuss findings in pancreas

Published in Obesity and Diabetes Week, March 30th, 2009

According to recent research from the United States, "We have generated a transgenic mouse model (MIP-luc) that allows real-time imaging of insulin-secreting pancreatic beta cells in living mice. The beta cells of MIP-luc transgenic mice emit a light signal that can be visualized externally by bioluminescent imaging using specialized equipment."

"In order to determine whether the intensity of the bioluminescent signal accurately reflects changes in beta-cell mass rather than simply transcriptional modulation of the mouse insulin I promoter-luciferase transgene, we examined the correlation between the bioluminescent signal and the beta-cell mass in MIP-luc mice fed a...

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