Obesity
Research from INSERM broadens understanding of obesity
Published in Obesity and Diabetes Week, April 6th, 2009
According to recent research from Grenoble, France, "Besides its well recognized role in lipid and carbohydrate metabolisms, glycerol is involved in the regulation of cellular energy homeostasis via glycerol-3-phosphate, a key metabolite in the translocation of reducing power across the mitochondrial inner membrane with mitochondrial glycerol-3-phosphate dehydrogenase. Here, we report a high rate of gluconeogenesis from glycerol and fatty acid oxidation in hepatocytes from Lou/C, a peculiar rat strain derived from Wistar, which is resistant to age- and diet-related obesity."
"This feature, associated with elevated cellular respiration and cytosolic ATP/ADP and...
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