Life Sciences

Report summarizes life sciences study findings from K. Eckardt and co-researchers

Published in Obesity and Diabetes Week, April 13th, 2009

According to recent research published in the journal Diabetologia, "Cannabinoid type 1 receptor (CB1R) antagonists such as rimonabant (Rim) represent a novel approach to treat obesity and related metabolic disorders. Recent data suggest that endocannabinoids are also produced by human adipocytes."

"Here we studied the potential involvement of endocannabinoids in the negative crosstalk between fat and muscle. The protein level of CB1R in human skeletal muscle cells (SkM) during differentiation was analysed using western blotting. SkM were treated with adipocyte-conditioned medium (CM) or anandamide (AEA) in combination with the CB1R antagonists Rim or AM251, and...

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Source: Obesity and Diabetes Week (2009-04-13)

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