Obesity and Diabetes
Studies from University of British Columbia reveal new findings on obesity and diabetes
Published in Obesity and Diabetes Week, April 20th, 2009
According to a study from Vancouver, Canada, "The endopeptidase dipeptidyl peptidase-IV (DPP-IV) has been shown to NH2-terminally truncate incretin hormones, glucose-dependent insulinotropic polypeptide, and glucagon-like peptide-1, thus ablating their ability to potentiate glucose-stimulated insulin secretion. Increasing the circulating levels of incretins through administration of DPP-IV inhibitors has therefore been introduced as a therapeutic approach for the treatment of type 2 diabetes."
"DPP-IV inhibitor treatment has also been shown to preserve islet. mass in rodent models of type 1 diabetes. The current. Study was initiated to define the effects of the DPP-IV...
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