Published in Obesity and Diabetes Week, May 25th, 2009
"Am J Physiol Endocrinol Metab 296: E690-E701, 2009. First published January 13, 2009; doi:10.1152/ajpendo.90525.2008.-There are strong links between obesity, elevated free fatty acids, and type 2 diabetes. Specifically, the saturated fatty acid palmitate has pleiotropic effects on beta-cell function and survival. In the present study, we sought to determine the mechanism by which palmitate affects intracellular Ca2+, and in particular the role of the...
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