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World Journal of Gastroenterology

Hyperferritinemia is another surrogate marker of advanced liver disease

Published in Obesity and Diabetes Week, May 25th, 2009

High serum ferritin, being a hallmark of hereditary hemochromatosis , is frequently found in chronic hepatitis C, alcoholic or non-alcoholic steatohepatitis and non-alcoholic fatty liver disease patients . A study in Italy has investigated the link between ferritin and steatosis in a non-obese cohort of non-alcoholic patients. In southern European populations, high ferritin levels, after exclusion of diagnosis of HH, represent a risk factor for steatosis and clinical relevance, being associated with low platelet count.

Patients with chronic hepatitis C virus (HCV) infection often have elevated serum iron indices, but these do not accurately reflect hepatic iron content,...

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