Diabetes

Research on diabetes described by scientists at University of Ulster

Published in Obesity and Diabetes Week, June 29th, 2009

"Enzyme-resistant glucagon-like peptide-1 (GLP-1) receptor agonists and GIP receptor antagonists have been proposed to have therapeutic potential for the treatment of type 2 diabetes. Such benefits are based on actions mediated primarily through stimulation of insulin secretion or alleviation of insulin resistance respectively," scientists in North Ireland report.

"This study examined the long-term actions of the stable GLP-1 receptor agonist (d-Ala(8))GLP-1 and the GIP receptor antagonist (Pro(3))GIP alone and in combination in high fat-fed mice. Mice on high-fat diet for 155 days were injected once daily with (d-Ala(8))GLP-1 or (Pro(3))GIP (25 nmol/kg body weight) for...

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Source: Obesity and Diabetes Week (2009-06-29)

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