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Obesity & Diabetes Week

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Hyperglycemia



Researchers from University of Hong Kong publish new studies and findings in the area of hyperglycemia



July 6th, 2009

According to recent research from Hong Kong, People's Republic of China, "Endothelial dysfunction is a key event that links obesity, diabetes, hypertension, and cardiovascular diseases. The aim of the present study was to examine the protective effect of the alkaloid drug berberine against hyperglycemia-induced cellular injury and endothelial dysfunction."

"In both cultured endothelial cells and blood vessels isolated from rat aorta, berberine concentration dependently enhanced phosphorylation of endothelial nitric oxide synthase (eNOS) at Ser(1177) and promoted the association of eNOS with heat shock protein 90 (HSP90), leading to an increased production of nitric...


Source: Obesity & Diabetes Week (2009-07-06)

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