Obesity and Diabetes
Researchers from Amgen, Inc. detail new studies and findings in the area of obesity and diabetes
Published in Obesity and Diabetes Week, July 13th, 2009
According to recent research from the United States, "11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) is considered to contribute to the aetiology of the metabolic syndrome, and specific inhibitors have begun to emerge as treatments for insulin resistance and other facets of the syndrome, including atherosclerosis. Given the role of glucocorticoids and 11 beta-HSD1 in the anti-inflammatory response and the involvement of inflammation in the development of atherosclerosis, 11 beta-HSD1 inhibition may exacerbate atherosclerosis."
"Our aim was to investigate in vivo the effects of a specific 11 beta-HSD1 inhibitor (2922) on atherosclerosis while assessing...
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