World Journal of Gastroenterology

Pluronic L-81 is a potential anti-diabetic drug?

Published in Obesity and Diabetes Week, July 20th, 2009

Pluronic surfactants are synthetic copolymers based on ethylene oxide and propylene oxide. It has been reported that a nonionic L-81, effectively inhibits absorption of dietary lipids from the intestine and secretion of VLDL and LDL from the liver. Although L-81 is a potent anti-obesity drug, its potential in alleviating obesity-induced insulin resistance and type 2 diabetes has not been fully explored.

A research article to be published on June 28, 2009 in the World Journal of Gastroenterology addresses this question. The research group led by Prof. Lin from the Department of Chemistry of the University of Hong Kong constructed db/db mice to investigate the potential...

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Source: Obesity and Diabetes Week (2009-07-20)

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