Obesity and Diabetes

Research from University of Pecs reveals new findings on obesity and diabetes

Published in Obesity and Diabetes Week, September 7th, 2009

"Cocaine- and amphetamine-regulated transcript (CART) peptide is expressed in brain areas involved in homeostatic regulation and reward. CART has been shown to reduce food intake, but the underlying mechanisms and the relevance of this effect on obesity yet remain unknown," researchers in Pecs, Hungary report.

"Therefore, we used immunohistochemistry to investigate the expression of CART peptide in various brain regions of the obese Otsuka Long Evans Tokushima Fatty (OLETF) rats lacking the CCK-1 receptor. Analysis revealed that whereas the distribution of CART-peptide immunoreactive neurons and axonal networks was identical in OLETF rats and lean controls, the...

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Source: Obesity and Diabetes Week (2009-09-07)

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