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From fat to chronic inflammation

Published in Obesity and Diabetes Week, September 14th, 2009

Researchers may have found a key ingredient in the recipe that leads from obesity to chronic low-grade inflammation, according to a report in the September issue of Cell Metabolism, a Cell Press publication.

Chronic inflammation within fat tissue is now recognized as a contributor to the many ill health consequences that come with obesity, from diabetes to cardiovascular disease, explains Yuichi Oike of Kumamoto University in Japan. The new discovery may therefore point to a targeted therapy designed to limit the health impact of the obesity epidemic, the researchers say.

The new culprit Oike's team identifies is a fat-derived protein called...

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