Obesity

Researchers from Leiden University describe findings in obesity

Published in Obesity and Diabetes Week, September 21st, 2009

According to recent research from Netherlands, "The pituitary-adrenal ensemble of obesehumans is marked by increased urinary excretion of cortisol and its metabolites in the face of normal circulating cortisol levels. For better understanding of the (patho) physiological meaning of these changes, the mechanistic underpinnings need to be clarified."

"and Methods: We investigated 17 obese women [body mass index (BMI) 30-39.4 kg/m(2)] and 14 normal women (BMI, 18.3-24.8 kg/m(2)) who underwent 24-h blood sampling at 10-min intervals, and plasma ACTH and cortisol concentrations were measured with sensitive assays. Data were analyzed with a new deconvolution program,...

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Source: Obesity and Diabetes Week (2009-09-21)

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