Obesity and Diabetes

Reports from University of Lyon add new data to research in obesity and diabetes

Published in Obesity and Diabetes Week, September 21st, 2009

"One of the major processes by which insulin exerts its multiple biological actions is through gene expression regulation. Thus, the identification of transcription factors affected by insulin in target tissues represents an important challenge," scientists writing in the journal Diabetologia report.

"The aim of the present study was to gain a greater insight into this issue through the identification of transcription factor genes with insulin-regulated expression in human skeletal muscle. Using microarray analysis, we defined the sets of genes modulated during a 3 h hyperinsulinaemic-euglycaemic clamp (2 mU min(-1) kg(-1)) in the skeletal muscle of...

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Source: Obesity and Diabetes Week (2009-09-21)

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