Published in Obesity and Diabetes Week, September 21st, 2009
"In this study, we determined whether Mstn disruption could prevent the development of insulin resistance, proatherogenic dyslipidemia, and atherogenesis. C57BL/6 Ldtr(-/-) mice were cross-bred with C57BL/6 Mstn(-/-) mice for > 10 generations to generate Mstn(-/-)/Ldlr(-/-) double-knockout mice. The effects of high-fat/high-cholesterol diet on body composition, plasma lipids,...
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