Obesity and Diabetes

Scientists at Boston University, Medical Department publish new data on obesity and diabetes

Published in Obesity and Diabetes Week, September 21st, 2009

According to recent research published in the journal Diabetes, "Insulin-resistant states, such as obesity and type 2 diabetes, contribute substantially to accelerated atherogenesis. Null imitations of myostatin (Mstn) are associated with increased muscle mass and decreased fat mass."

"In this study, we determined whether Mstn disruption could prevent the development of insulin resistance, proatherogenic dyslipidemia, and atherogenesis. C57BL/6 Ldtr(-/-) mice were cross-bred with C57BL/6 Mstn(-/-) mice for > 10 generations to generate Mstn(-/-)/Ldlr(-/-) double-knockout mice. The effects of high-fat/high-cholesterol diet on body composition, plasma lipids,...

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Source: Obesity and Diabetes Week (2009-09-21)

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