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Diabetes

Studies from C. Murgia et al have provided new data on diabetes

Published in Obesity and Diabetes Week, September 21st, 2009

"Zinc is abundant in pancreas, being required by endocrine islet cells for hormone secretion and by exocrine acinar cells as pancreatic juice component. ZnT8 is a member of the SLC30A family of zinc transporters whose overexpression in cultured pancreatic beta cells leads to increased insulin secretion in response to glucose, suggesting a possible role in regulating glycemia," scientists writing in the journal Nutrition Metabolism and Cardiovascular Diseases report.

"ZnT8 was therefore proposed as a therapeutic target for diabetes, and recent genome-wide association studies identified polymorphisms in the ZNT8 gene conferring increased type 2 diabetes risk. As...

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