Gilead Sciences, Inc.
Pivotal Data Demonstrating Efficacy of Darusentan in Treating Resistant Hypertension Published in the Lancet
Published in Obesity and Diabetes Week, September 28th, 2009
Gilead Sciences, Inc. (Nasdaq:GILD) announced the publication of data from DAR-311 (DORADO), a Phase III clinical trial evaluating the company's once-daily oral endothelin receptor antagonist (ERA) darusentan as an add-on treatment for resistant hypertension, defined as the failure to achieve blood pressure goal while adhering to full doses of an appropriate three (or more) drug antihypertensive regimen that includes a diuretic. The results of the DAR-311 study, published online and in an upcoming edition of The Lancet, show that darusentan was effective at reducing trough sitting and mean 24-hour systolic blood pressure (SBP) and diastolic blood pressure (DBP) after 14 weeks of treatment...
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