Published in Obesity and Diabetes Week, October 12th, 2009
"This study examined the hypothesis that PTP1B is a negative regulator of the cardiovascular effects of leptin. PTP1B knockout mice had lower body fat but higher mean arterial pressure (116 +/- 5 versus 105 +/- 5 mm Hg, P< 0.05) than controls. Leptin infusion produced a...
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