Obesity and Diabetes
Studies from University of Groningen yield new information about obesity and diabetes
Published in Obesity and Diabetes Week, October 26th, 2009
According to recent research published in the journal Diabetes Obesity & Metabolism, "Inhibition of the acetyl-CoA carboxylase (ACC) system, consisting of the isozymes ACC1 and ACC2, may be beneficial for treatment of insulin resistance and/or obesity by interfering with de novo lipogenesis and beta-oxidation. We have evaluated effects of pharmacological inhibition of ACC by soraphen (SP) on high fat (HF) diet-induced insulin resistance in mice."
"Male C57Bl6/J mice were fed control chow, a HF diet or a HF diet supplemented with SP (50 or 100 mg/kg/day). Body weight gain and total body fat content of SP-treated animals were significantly reduced compared with...
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