Obesity & Diabetes Week
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Ischemia
New ischemia study findings have been reported by H. Kilter and colleagues
November 9th, 2009
"Results on the cardiovascular effects of PPAR-gamma agonists are conflicting. On one hand, it was suggested that the PPAR-gamma agonist rosiglitazone may increase the risk of cardiovascular events," scientists writing in the journal Diabetes Obesity & Metabolism report. "On the other hand, PPAR-gamma agonists reduce myocardial infarct size and improve myocardial function during ischemia/reperfusion in animal studies in vivo. However, the mechanism of this effect is unclear, and it is open if PPAR-gamma agonists have a direct effect on cardiac myocyte survival in ischemia/reperfusion. The aim of this study was to determine the effect of the PPAR-gamma agonist...
Source: Obesity & Diabetes Week (2009-11-09)
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