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Obesity

Findings from INSERM advance knowledge in obesity

Published in Obesity and Diabetes Week, December 14th, 2009

According to a study from Paris, France, "Macrophages accumulate in adipose tissue and possibly participate in metabolic complications in obesity. Macrophage number varies with adipose tissue site and weight loss, but whether this is accompanied by phenotypic changes is unknown."

"The objective of the study was to characterize the activation state of adipose tissue macrophages in human obesity. We performed a single-center prospective study. Paired biopsies of sc and omental adipose tissue were obtained during gastric surgery in 16 premenopausal obese women (aged 41.1 +/- 8.6 yr; body mass index 43.8 +/- 3.4 kg/m(2)). Subcutaneous adipose tissue biopsies were obtained 3...

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