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Obesity and Diabetes

Data from S. Pechlivanis et al provide new insights into obesity and diabetes

Published in Obesity and Diabetes Week, February 15th, 2010

According to recent research from Heidelberg, Germany, "Obesity has been related to an increased risk of colorectal cancer (CRC). Adipokines produced by the adipose tissue are directly linked to obesity and may thus contribute to the pathogenesis of CRC."

"We hypothesized that potentially functional polymorphisms in the adipokine genes leptin (LEP), leptin receptor (LEPR), resistin (RETN). and adiponectin (ADIPOQ) may be associated with CRC. We studied the association of four putatively functional single nuclecitide polyworphisms (SNPs) with CRC risk using a hospital-based study design with 702 cases and 752 controls from the Czech Republic. We used likelihood ratio...

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