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Antiretroviral

Researchers from University Hospital report recent findings in antiretroviral

Published in Obesity and Diabetes Week, February 15th, 2010

"Studies carried Out to assess the effects of antiretroviral drugs (ARV) in HIV-1 infected pregnant women have demonstrated carbohydrate intolerance. Some reports also refer to the effect of disturbances in the expression of the insulin-like growth factor (IGF) system on pancreas beta-cell function in humans and IGF-2/ApaI polymorphisms have been associated with obesity and features of the metabolic syndromes. in the present study, we tested the association between IGF-2/ApaI genotype and hyperglycemia in HIV-1 infected pregnant women receiving ARV," researchers in Ribeirao Preto, Brazil report.

"We studied IGF-2/ApaI polymorphism in 87 healthy pregnant women, 43 HIV-1...

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