Life Sciences
New findings from University of Memphis, Department of Chemistry in the area of life sciences described
Published in Obesity and Diabetes Week, February 22nd, 2010
Scientists discuss in 'Characterization of non-lipid autotaxin inhibitors' new findings in life sciences. "Autotaxin (ATX) is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (NPP) family and is a lysophospholipase D that cleaves the choline headgroup from lysophosphatidylcholine to generate the bioactive lipid lysophosphatidic acid (LPA). Enhanced expression of ATX and specific receptors for LPA in numerous cancer cell types has created an interest in studying ATX as a potential chemotherapeutic target," scientists writing in the journal Bioorganic & Medicinal Chemistry report.
"Likewise, ATX has been linked to several additional human diseases...
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