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Aneuploidy

Scientists at Baylor College of Medicine, College of Medicine discuss research in aneuploidy

Published in Obesity and Diabetes Week, March 1st, 2010

"We Sought to evaluate the influence of maternal body mass index (BMI) on sonographic detection employing data from the FaSTER trial. Unselected singleton pregnancies underwent detailed genetic sonogram to evaluate for structural fetal anomalies and soft markers for aneuploidy," investigators in the United States report.

"BMI (kg/m(2)) were calculated from reported initial visit values. Sensitivity, specificity, false positive and false negative rates (FPR and FNR), likelihood ratio, detection rates, and a missed diagnosis rate (MDR: FNR + marker recorded as 'missing'/N) were calculated. Eight thousand five hundred and fifty-five patients with complete BMI information...

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