Pharmacokinetics
New pharmacokinetics study findings have been reported from Albany Medical College, Medical College
Published in Obesity and Diabetes Week, April 19th, 2010
"We have recently shown that intranasal administration of mouse [D-Leu-4]-OB3 reconstituted in Intravail ® to male Swiss Webster mice resulted in significantly higher bioavailability than commonly used injection methods of delivery. The absorption profile associated with intranasal delivery of mouse [D-Leu-4]-OB3 showed an early peak representing rapid uptake across the nasal mucosa, and a later peak suggesting a gastrointestinal site of absorption," researchers in the United States report.
"In the present study, we show that gastrointestinal absorption of mouse [D-Leu-4]-OB3 does occur, and that reformulation of mouse [D-Leu-4-OB3 with Intravail ®...
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