Carboxylic Ester Hydrolases

Scientists at Zhengzhou University discuss research in carboxylic ester hydrolases

Published in Obesity and Diabetes Week, May 24th, 2010

According to recent research published in the journal Hormone and Metabolic Research, "Elevated plasma levels of free fatty acids (FFAs) are thought to restrict glucose utilization and induce insulin resistance. Plasma FFA concentrations are primarily governed by lipolysis in adipocytes."

"Perilipin surrounds the lipid droplet in adipocytes and has a dual role in lipolysis regulation. Perilipin null mice studied by two independent laboratories exhibited similar phenotypes of reduced adipose mass and resistance to diet-induced obesity, but have inconsistent metabolic parameters such as plasma levels of FFA, glucose, and insulin. This discrepancy may be due to...

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Source: Obesity and Diabetes Week (2010-05-24)

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