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Cysteine Endopeptidases

New cysteine endopeptidases study findings recently were published by researchers at Wayne State University

Published in Obesity and Diabetes Week, May 24th, 2010

Current study results from the report, 'Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation,' have been published. "Complications of diabetes mellitus (DM) weigh heavily upon the endothelium that ultimately affect multiple organ systems. These concerns call for innovative treatment strategies that employ molecular pathways responsible for cell survival and longevity," scientists in the United States report.

"Here we show in a clinically relevant model of DM with elevated D-glucose that endothelial cell (EC) SIRT1 is vital for the prevention of early membrane apoptotic...

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