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Adipokine Receptors

Research from T.K. Felder and colleagues has provided new data on adipokine receptors

Published in Obesity and Diabetes Week, May 24th, 2010

Research findings, 'Hepatic adiponectin receptors (ADIPOR) 1 and 2 mRNA and their relation to insulin resistance in obese humans,' are discussed in a new report. According to recent research from Salzburg, Austria, "Adiponectin signalling attenuates insulin resistance (IR) and steatosis hepatis in animal models. As adiponectin receptor (ADIPOR)1 and ADIPOR2 are critical components in the adiponectin signalling cascade, we studied hepatic ADIPOR1/2 mRNA levels in humans and their relation to IR."

"We determined metabolic risk factors and levels of hepatic mRNA transcribed from ADIPOR1, ADIPOR2 and FOXO1, a putative up-stream regulator, in 43 and 34 obese subjects with...

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