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Cytomegalovirus

Research on cytomegalovirus published by scientists at Mayo Clinic

Published in Obesity and Diabetes Week, May 24th, 2010

According to a study from the United States, "Cytomegalovirus (CMV)-specific cellular immunity is essential in controlling CMV infection after transplantation. We investigated whether CMV-specific T cell levels predict CMV DNAemia after kidney transplantation."

"Using cytokine-flow cytometry, we enumerated interferon-gamma producing CMV-specific CD4+ and CD8+ T cells at serial time points among CMV-mismatched (D+/R-) and seropositive (R+) kidney recipients who received 3 months of valganciclovir prophylaxis. Among 44 patients, eight (18%) developed CMV DNAemia at a mean (+/- SD) time of 151 (+/- 33) days after transplantation, including two (5%) with CMV syndrome and...

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