Published in Obesity and Diabetes Week, June 7th, 2010
"TZDs are agonists of the nuclear hormone receptor peroxisome proliferator-activated receptor-gamma (PPAR gamma), are peripheral insulin sensitizers, and have recently been reported to increase mitochondrial biogenesis in the central nervous system and dendritic spine density. We report a transcriptional profile of the TZD pioglitazone and the non-TZD PPAR gamma agonist GW347845 in primary cortical culture. We...
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