Diabetes
Findings from University of Auckland broaden understanding of diabetes
Published in Obesity and Diabetes Week, November 8th, 2010
In this recent study, researchers in Auckland, New Zealand conducted a study "To determine if there is an abrupt change in the frequency of intraislet T regulatory (Treg) cells in female nonobese diabetic (NOD) mice preceding and following spontaneous diabetes and during cyclophosphamide-accelerated disease. The frequency of intraislet CD4-positive Treg cells was analyzed between days 21 and 250, at onset, and at 1, 2, and 3 weeks of diabetes by dual-label immunohistochemistry."
"Tissues were also analyzed between days 0 and 14 after injection of cyclophosphamide or diluent. In the spontaneous group, intraislet Treg cells were first observed on day 30 in CD4 T cells and...
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