Diabetes
Investigators at University of Regensburg, Department of Internal Medicine I target diabetes
Published in Obesity and Diabetes Week, November 22nd, 2010
Fresh data on diabetes are presented in the report 'C1q/TNF-related protein-3 represents a novel and endogenous lipopolysaccharide antagonist of the adipose tissue.' "Proteins secreted by adipocytes (adipokines) play an important role in the pathophysiology of type 2 diabetes mellitus and the associated chronic and low-grade state of inflammation. It was the aim to characterize the antiinflammatory potential of the new adipocytokine, C1q/TNF-related protein-3 (CTRP-3), which shows structural homologies to the pleiotropic adipocytokine adiponectin. mRNA and protein expression of CTRP-3 was analyzed by RT-PCR and Western blot," investigators in Regensburg, Germany report.
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