Published in Obesity and Diabetes Week, January 17th, 2011
"Rats received sham surgery (SHAM), OVX, or OVX with hormonal replacement (17 beta-estradiol, 2 mu g per 4 d; OVX + E) and were infused with vehicle or amylin (50 mu g/kg. d) for 28 d. Amylin reduced body weight (5.1 +/- 1.1%) and food intake (10.9 +/- 3.4%) in SHAM rats but was twice as efficacious in OVX rats in reducing weight (11.2 +/- 1.9%) and food intake (23.0 +/- 2.0%). There were no differences between amylin-treated...
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