Obesity
New Obesity Study Findings Recently Were Reported by Researchers at Columbus Children's Hospital
Published in Obesity and Diabetes Week, March 7th, 2011
2011 MAR 7 -- According to recent research published in the journal Proceedings of the National Academy of Sciences of the United States of America, "In yeast, Sir2 family proteins (sirtuins) regulate gene silencing, recombination, DNA repair, and aging via histone deacetylation. Most of the seven mammalian sirtuins (Sirt1-Sirt7) have been implicated as NAD(+)-dependent protein deacetylases with targets ranging from transcriptional regulators to metabolic enzymes."
"We report that neural-specific deletion of sirtuin 6 (Sirt6) in mice leads to postnatal growth retardation due to somatotropic attenuation through low growth hormone (GH) and insulin-like...
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