Diabetes
Findings from University of Pennsylvania Provide New Insights into Diabetes
Published in Obesity and Diabetes Week, June 6th, 2011
2011 JUN 6 -- "Although adipocyte-derived murine resistin links insulin resistance to obesity, the role of human resistin, predominantly expressed in mononuclear cells and induced by inflammatory signals, remains unclear. Given the mounting evidence that obesity and type 2 diabetes are inflammatory diseases, we sought to determine the relationship between inflammatory increases in human resistin and insulin resistance," scientists in Philadelphia, United States report.
"To investigate the role of human resistin on glucose homeostasis in inflammatory states, we generated mice lacking murine resistin but transgenic for a bacterial artificial chromosome...
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