Published in Obesity and Diabetes Week, September 5th, 2011
"Studies were conducted with Cpd-A to examine the effects on glucose-lowering efficacy, its effects in combination with a dipeptidyl peptidase-4 (DPP-4) inhibitor, and the extent and reversibility of alpha cell hypertrophy associated with GCGR antagonism in mouse models. Chronic treatment with Cpd-A resulted in effective and sustained glucose lowering in mouse models in which...
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