Obesity

Data on Obesity Discussed by W.C. Stewart and Colleagues

Published in Obesity and Diabetes Week, September 26th, 2011

2011 SEP 26 -- "Many studies from our laboratories and others have shown that STAT5 expression and activity are increased during adipogenesis of murine and human adipocytes. Ectopic expression of STAT5A in fibroblasts or preadipocytes can confer or enhance adipogenesis," scientists in Baton Rouge, Louisiana report.

"To determine whether STAT5A also plays a role in adipogenesis in vivo, we injected athymic mice with Swiss 3T3 cells expressing an empty pBABE retrovirus, Swiss cells expressing a pBABE retrovirus-containing STAT5A, or 3T3-F442A preadipocytes. Athymic mice injected with either 3T3-F442A cells or Swiss 3T3 cells expressing STAT5A resulted in fat...

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Source: Obesity and Diabetes Week (2011-09-26)

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