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Type 2 Diabetes Mellitus

Findings from Instituto de Salud Carlos III Advance Knowledge in Type 2 Diabetes Mellitus

Published in Obesity and Diabetes Week, December 12th, 2011

2011 DEC 12 -- According to the authors of a study from Malaga, Spain, "Six-transmembrane protein of prostate 2 (STAMP2) is a counter-regulator of inflammation and insulin resistance according to findings in mice. However, there have been contradictory reports in humans."

"We aimed to explore STAMP2 in association with inflammatory and metabolic status of human obesity. Patients, and Methods: STAMP2 gene expression was analyzed in adipose tissue samples (171 visceral and 67 sc depots) and during human preadipocyte differentiation. Human adipocytes were treated with macrophage-conditioned medium, TNF-alpha, and rosiglitazone. In visceral adipose tissue,...

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