Diabetes
Bile acids may hold clue to treat heart disease
Published in Obesity and Diabetes Week, December 19th, 2011
2011 DEC 19 -- Heart disease is a major cause of death in industrialised countries, and is strongly associated with obesity and diabetes. Many scientists believe that what links these conditions is a chronic, low-grade inflammation. The current study, published in the scientific journal Cell Metabolism (December 6, 2011), supports that theory by demonstrating that a modified bile acid called INT-777 prevents atherosclerosis, the build-up of fatty plaques in the walls of arteries, and a leading cause of heart disease-and that it does so by exerting an anti-inflammatory effect.
INT-777 activates a receptor in the membrane of gut cells called TGR5, and in so...
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